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Real members of MyPrurigoTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

What if you will. Ot take steroids. .

A MyPrurigoTeam Member asked a question 💭
Southfield, MI

Taking dupixent twice monthly injection , plus Allegra, and other oral meds. Alcohol seems to improve e symptioms, possibly by numbing my brain. I get close to intolerable but ing inside arms, legs, limbs entire torso and genital areas. Itching occurs in all of these places also. It’s tormenting. Scan you still take Dupixen after being prescribed Methotrexate.

March 22
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How Are Prurigo Nodularis and Lupus Related? Read Article...
A MyPrurigoTeam Member

I have had PN foraprox 3-4 years. Dx and treatment began six months ago. Outdoor never speak or get messages to him or even speak to any office people for the past 6months either with the exception of attending an office visit. I changed doctors. My new doc appears to be very young. I believe I can connect with the office by phone. Meanwhile, I have NO patience to wait for anything in my entire life. I’m angry, reactive, using foul language and projecting it onto others .. I am an educated woman with a master’s degree in clinical social work. I cannot control my experience of this horrendous PN. IM WAITING FOR MY NEW DOC TO GET BACK TO ME THIS COMING WEEK. HELP

March 22
MyPrurigoTeam

Can you take Dupixent after being prescribed methotrexate?

It's really important to discuss this specific combination with your doctor, as they know your complete medical history. Both Dupixent and methotrexate are immune-modifying treatments used for prurigo nodularis, but they work differently in the body.

Your doctor Show Full Answer

Can you take Dupixent after being prescribed methotrexate?

It's really important to discuss this specific combination with your doctor, as they know your complete medical history. Both Dupixent and methotrexate are immune-modifying treatments used for prurigo nodularis, but they work differently in the body.

Your doctor needs to evaluate whether combining these medications is safe and appropriate for your situation. They can also help determine if switching from one to the other makes more sense than using them together.

Regarding the severe itching you're experiencing across your body - this sounds incredibly difficult to manage. While alcohol might seem to provide temporary relief, it's not a recommended treatment approach and could potentially interfere with your medications or worsen symptoms over time.

Here are some treatment options that might help with your intense itching:

* Dupixent (which you're already taking) - though it may take 2-4 months to see maximum benefit
* Topical treatments like capsaicin creams for nerve-related itching
* Antihistamines (you mentioned Allegra)
* Neuromodulating medications like gabapentin or pregabalin that reduce itch signal transmission
* Phototherapy as an additional option

If your current treatment plan isn't providing enough relief after giving it adequate time, talk to your doctor about adjusting your approach or adding complementary therapies.

March 22

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