If in your case the issue is related to proton pump inhibitor medications, there are treatments to restore kidney function as far as I know. It would be amazing if improving your kidney function could help you get out of PN! 🤞
I've read that they're treating some PN cases with microbiota. I can't find the article right now, but it's supposed to help with underlying problems. That would be fantastic

Dupixent isn’t a cure but for me it has helped with healing and itching. The only thing that has given me the best results so far.

I have been on Dupixent since April 2023 and methotrexate since 10/22. I also take a daily folic acid tablet. My arms wetre absolutely covered in nodules. Today, 11/19/2023 I have zero nodules on my right arm and only three on my right arm that are almost healed. It has been an absolute miracle❤️ I make sure to keep them moist with alternating vaseline, Mupirocin, polysporin. Rotating seems to help more. If they itched really bad I would put CVS Lidocaine Wound Gel on them. Relieved itch immediately for a while. I also found not touching and covering two at a time would really speed healing on those two. I could pick and scratch away at the others but at least I was healing some. I hope everyone sees the results I have. Back to sleeveless shirts again💃💃

I’ve been on it for about 8 months. I would say that it’s working somewhat, but certainly not a cure. I find that the best Rx I have tried is the SUN! (Although risky for other reasons, of course).

I notice a huge difference with Dupixent.