Answer Summary

Members confirmed that prurigo nodularis lesions frequently return to the same spots, with many describing a frustrating cycle where healed... Read more

Members confirmed that prurigo nodularis lesions frequently return to the same spots, with many describing a frustrating cycle where healed sores begin to itch, get scratched, and then reappear in identical locations or spread to new areas. Several members shared that scratching weakens the skin and attracts mast cells to those vulnerable spots, making recurrence more likely, while others noted that intense itching often signals a new lesion forming even before it's visible. A recurring theme was the emotional toll of this never-ending cycle, with members finding comfort in the shared struggle and grateful for the friendships formed through the community.