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A MyPrurigoTeam Member asked a question 💭
Tooele, UT
March 26, 2025
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Answer Summary

Members shared overwhelmingly positive experiences with NAC (N-Acetyl-Cysteine) for managing itching, with many reporting that their... Read more

Members shared overwhelmingly positive experiences with NAC (N-Acetyl-Cysteine) for managing itching, with many reporting that their dermatologists prescribed 600mg twice daily to avoid drug interactions and prescription side effects. Several members described how NAC worked best when combined with antihistamines like Zyrtec or Pepcid, and many emphasized that breaking the itch-scratch cycle through behavioral strategies was just as important as medication. A recurring theme was gratitude for finding a natural, over-the-counter supplement that effectively calmed the nervous system and reduced itching, with members recommending the Nutracost brand and encouraging others to consult their dermatologist before trying it.

A MyPrurigoTeam Member

My dermatologist put me on NAC probably about a year ago. It has helped me a lot. She also put me on Pepcid 20 mg and Zyrtec 10 mg. She started me out on taking it 3 times a day. Then she decreased it to twice a day. Kept me on that dosage for about 6 months. Then she said I could decrease to once a day. But I take the Pepcid and NAC twice a day and the Zyrtec once a day. The itching has decreased significantly.

March 26, 2025
A MyPrurigoTeam Member

Thank you for the explanation. I noticed that it relaxes me, although I still have some itching. I'm also using Nutracost brand twice a day. I don't know if this is considered Holistic, but I prefer the natural remedies.

May 4, 2025
A MyPrurigoTeam Member

I was put on Pepcid twice a day, L-theanine 1-2 x/day, Beet Extract 1000mg (which I couldn't find, so I finally bought a real beet), & Allegra at night. My itching didn't decrease. Maybe she needed to increase the dosage of Pepcid. I will be meeting with the Ohysician's Assistance in 2 weeks. Good your treatment is working.🤗

March 26, 2025
A MyPrurigoTeam Member

My dermatologist recommended N-Acetyl-Cysteine for me. Their reasoning was that since I already had a good amount of prescription medications as part of my medical management. They felt that they wanted to avoid drug interactions as well as side effects. It has worked very well for me so far. The dose is 600 mg twice per day.

March 26, 2025
A MyPrurigoTeam Member

Cathy, I wanted you to know that I used Lubriderm Advanced Therapy lotion and am still using it after showering. It is very moisturizing and non-stickey. Thanks for posting what you use.

July 29, 2025

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