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Real members of MyPrurigoTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyPrurigoTeam Member asked a question 💭
Texas City, TX

Received offensive accusation. I do not scratch my sores. There is a reason these sores take forever and a day to heal and I would like to know why and I would also like to know why PN sufferers are accused of scratching and that is what causes the nodules, lesions and sores WHICH IS NOT TRUE IN MY CASE.

July 26, 2025 (edited)
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A MyPrurigoTeam Member

You all are so sweet, I wish I could help each and every one of you. I would take away all your pains and injuries, I would help us all touch our Creators heart that he wrap us in His protection and never let us down. Dear Jesus I know I'm not the best servant and lately have had some struggles and shortcomings but you hold all power and can deliver us all. Please put us in your secret place and shield us from all harm, hurt and danger. Care for us because without you we're adrift in the sea of life with no anchor or sails. We depend on you like defenseless animals needing shelter and care. Love us Jesus as your children and care for us as you care for those you love. In Jesus name I pray, Amen 🙏❤️‍🔥❤️⛵💫

August 25, 2025
A MyPrurigoTeam Member

I think they take so long because they come from way down in your skin, form a core. I know picking is wrong but they don't go away until that core is gone. Some of mine have little brown like seeds. They hurt and itch so bad I don't care.

July 26, 2025
A MyPrurigoTeam Member

I think that PN nodules take so long to heal because they affect all of the 7 layers of skin and have nerve involvement. I think dermatologists perform a punch biopsy for diagnosis because a punch biopsy involves all 7 layers of skin. I think that there is a lot of discussion regarding scratching, itching, and digging (picking). I think that these behaviors are a result of the desire or impulse to rid one's skin of the lesions. I remember when the dermatologist and I had a discussion about the itch scratch cycle; I felt embarrassed and defensive, even though they were very kind and gentle in their presentation. I had to examine my own behaviors and responses to my management of this disease. It was at that time that my dermatologist recommended N-Acetyl-Cysteine supplement to me. I immediately ordered it and I haven't stopped using it since.

July 26, 2025
A MyPrurigoTeam Member

And now AI BACKTRACKS

July 26, 2025
MyPrurigoTeam

Your frustration is completely valid. The healing process in PN is complex and involves more than just scratching. Research shows that people with PN have fundamental differences in their skin composition, including:

- More nerve fibers in the dermis (middle skin layer)
- Fewer nerve fibers in the epidermis (outer layer)
- Show Full Answer

Your frustration is completely valid. The healing process in PN is complex and involves more than just scratching. Research shows that people with PN have fundamental differences in their skin composition, including:

- More nerve fibers in the dermis (middle skin layer)
- Fewer nerve fibers in the epidermis (outer layer)
- Higher levels of inflammatory immune cells, including mast cells
- Increased histamine release These biological differences mean that PN nodules and sores can develop and persist even without scratching. The condition involves an overactive immune response and nervous system changes that can cause prolonged inflammation and delayed healing. It can take months or years for nodules to resolve, regardless of scratching behavior.

It's important that healthcare providers understand that PN is more complex than just an itch-scratch cycle and that patients deserve compassionate, evidence-based care that addresses the underlying biological mechanisms of the condition.

July 26, 2025

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