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Real members of MyPrurigoTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
August 23, 2025
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A MyPrurigoTeam Member

I didn't know Gabapentin was prescribed for PN, I was taking it for years for nerve pain due to cervical and lumbar issues but recently stopped. The only prescribed meds I've tried for PN were two different steroid ointments, mainly Clobetasol and it doesn't work for me. My scalp is the only area I have PN and I also have another skin thing that I believe is connected somehow , it's called lichensclerosus and ugh that's the pits too. Sorry that I'm rambling.

August 24, 2025
MyPrurigoTeam

Gabapentin is prescribed for PN because researchers believe people with the condition have more sensitive nerve fibers that contribute to itchiness. Gabapentin works by stopping nerve cells from activating, which helps block itch and pain signals from reaching the brain. As for Dupixent (dupilumab), it's actually the first Show Full Answer

Gabapentin is prescribed for PN because researchers believe people with the condition have more sensitive nerve fibers that contribute to itchiness. Gabapentin works by stopping nerve cells from activating, which helps block itch and pain signals from reaching the brain. As for Dupixent (dupilumab), it's actually the first FDA-approved medication specifically for PN. It works by reducing immune system responses that cause inflammation. Clinical studies have shown promising results - in one study with 64 participants, after 4 months:

• 45.3% experienced complete remission
• Those who didn't achieve complete remission still reported significant reduction in itching
• No serious side effects were reported

Dupixent is typically administered as an injection under the skin every 2-4 weeks.

August 23, 2025
A MyPrurigoTeam Member

Sometimes physicians prescribe medications that are considered "off label." This means that a drug is being used for an additional condition or diagnosis for which it was not initially meant to treat. Physicians use off label medications when there is enough evidence based on studies that it is effective. I'm wondering if the gabapentin because of its usage for nerve related pain.

October 3, 2025
A MyPrurigoTeam Member

My husband takes Gabapentin for his back pain. PN is not a nerve disease. It is a genetic disease from Chromosome 20 on the long leg. Gene IL-31. I think doctor's try to help their patients by treating symptoms instead of cause. Sometimes that is the best and sometimes it is not the best. If it works go for it. My husband can't make it without his gabapentin so go for it,

October 3, 2025
A MyPrurigoTeam Member

Lori, gabapentin is typically prescribed for nerve related pain. It could be that their physician could have prescribed it for PN related pain.

August 31, 2025

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