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Real members of MyPrurigoTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Dupixent. I have had some painful times but no positive? Would you do it? Only tests I have had are 2 nonspecific biopsies.

October 14, 2025
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A MyPrurigoTeam Member

Georgia, I'm going to respectfully suggest that prior to seeing a new dermatologist that you take the time to obtain your medical records from the previous dermatologist, to take along to your initial appointment. Another thought I have is to review your current dermatological situation with you primary care physician. If possible, I also encourage you to write a list of questions and concerns for the appointment, plus a list of your current and past medications. It may be helpful to provide your medical history as well. After all, physicians only provide patients with a limited amount of time so I think it is worthwhile to be prepared. Good luck. P.S. If you are able, maybe take a support person as a second set of ears and to take notes for you.

October 15, 2025
A MyPrurigoTeam Member

Thank you! I don't know with my age, the cost and no positive diagnosis. I see a new dermatologist this week but none seems to have much knowledge. I'm going to ask for further tests!

October 14, 2025
MyPrurigoTeam

Question: Should someone start Dupixent treatment for suspected PN without a definitive diagnosis?

Dupixent (dupilumab) is currently the only FDA-approved medication specifically for treating prurigo nodularis. In clinical studies, it has shown promising results - after 4 months of treatment, 45.3% of people experienced Show Full Answer

Question: Should someone start Dupixent treatment for suspected PN without a definitive diagnosis?

Dupixent (dupilumab) is currently the only FDA-approved medication specifically for treating prurigo nodularis. In clinical studies, it has shown promising results - after 4 months of treatment, 45.3% of people experienced complete remission, with many others seeing significant reduction in itching. The medication has been reported to have minimal serious side effects. Most people need to take Dupixent consistently for about two months to see results, and four months for maximum benefit. While the decision to start any treatment is personal and should be made with your healthcare team, it's worth noting that finding effective treatment often requires patience and multiple attempts. If you're uncertain about the diagnosis, you may want to seek an additional opinion from a dermatologist who specializes in PN before starting treatment.

October 14, 2025

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