Connect with others who understand.

  • Learn from expert-reviewed resources
  • Real advice from people who’ve been there
  • People who understand what you’re going through
Sign Up Log In
Powered By
Real members of MyPrurigoTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
A MyPrurigoTeam Member asked a question 💭
Berea, OH
August 15
 · 
Reactions
Prurigo Nodularis Histology Basics: What Can You See With a Microscope? Read Article...
A MyPrurigoTeam Member

I also had two biopsies and both came back specific for "itchy bumps" disease.

August 16 (edited)
A MyPrurigoTeam Member

Hi Marc! The biopsies were to diagnose what these sores are. No, I have never been confirmed purigo nodularis. The doctors took the non-specific as a positive for purigo nodularis. Wait a minute and I get ignored.

August 16
MyPrurigoTeam

It's completely understandable to want more answers — two non-specific biopsies can feel really frustrating when you're dealing with something as intense as prurigo nodularis!

Beyond biopsies, doctors can order additional tests to help rule out other triggers or underlying causes contributing to PN. These include:

- Show Full Answer

It's completely understandable to want more answers — two non-specific biopsies can feel really frustrating when you're dealing with something as intense as prurigo nodularis!

Beyond biopsies, doctors can order additional tests to help rule out other triggers or underlying causes contributing to PN. These include:

- Complete blood count (CBC) — checks for signs of infection, including parasitic infections
- Kidney, liver, and thyroid function tests — to check organ health
- Hemoglobin A1c — checks blood sugar levels
- Hepatitis B, hepatitis C, and HIV screening — these can increase PN risk
- Direct immunofluorescence staining — a special biopsy test that looks at immune activity in the skin It's worth having a direct conversation with a dermatologist about requesting these broader tests. Being specific about concerns — like ruling out fungal or parasitic involvement — can help guide what gets ordered.

A pathologist can also use different staining techniques on biopsy samples to look for specific cell types or reactions, so asking whether additional staining was done on previous samples is a fair question too!

August 15
A MyPrurigoTeam Member

I’m wondering. Did anybody get these things after the COVID shot because I never had these until then.

August 31
A MyPrurigoTeam Member

Georgia, I forget, have you ever been on a biologic for your PN, either Dupixent or Nemluvio? If not, IMHO, you should demand your derm put you on one or the other.

August 17

Related Questions

View All