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Real members of MyPrurigoTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Anyone recommend capsaicin for back nodules severe itch? if so which cream???

A MyPrurigoTeam Member asked a question 💭
New York, NY
September 6
 · 
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MyPrurigoTeam

Capsaicin is definitely worth exploring for PN-related itch! It's the compound that makes chili peppers hot, and it has shown real promise for reducing skin inflammation and itch in prurigo nodularis.

A small but notable study had 33 people with PN apply capsaicin cream (0.25%–0.3% concentration) four to six times daily Show Full Answer

Capsaicin is definitely worth exploring for PN-related itch! It's the compound that makes chili peppers hot, and it has shown real promise for reducing skin inflammation and itch in prurigo nodularis.

A small but notable study had 33 people with PN apply capsaicin cream (0.25%–0.3% concentration) four to six times daily. After just 12 days, itching was eliminated in all participants and lesions began to heal. That's pretty encouraging, even if larger studies are still needed. Some over-the-counter capsaicin products that may help include:

- Salonpas Hot
- Capzasin-HP
- Zostrix HP

A few important things to keep in mind:

- Apply consistently — results took nearly two weeks in the study
- About half of participants saw symptoms return within two months of stopping, so ongoing use may be needed
- Always check with your dermatologist before starting, especially for a hard-to-reach area like your back
- Capsaicin can cause a burning sensation when first applied — this is normal but worth knowing!

September 6
A MyPrurigoTeam Member

I use Capsaicin nightly now and it truly makes a difference. My flare ups seem to stay on my arms so I put a layer of the cream on my arms the I put on sleeves so that I don't touch it. However, some little monsters are now showing up on my left leg which I will do the same and sleep with leggings on.

2 days ago
A MyPrurigoTeam Member

I have used capsaicin successfully several times. It is a challenge because initially it causes burning/itch, which lessens over time. Use gloves and avoid any contact with eyes .My last flareup was in July and I used for 2 weeks, now in remission. I purchased the Rugby capsaicin 0.075% from Amazon. Other brands were too weak.

September 8

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which capsaicin cream to help severe itch at night???

A MyPrurigoTeam Member asked a question 💭
New York, NY
4 days ago

45% Find Itch Relief From Ruxolitinib Cream in Clinical Trials
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