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A MyPrurigoTeam Member asked a question 💭
Austin, TX
September 17, 2025
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MyPrurigoTeam

While both tests can be effective, dermoscopy is often preferred as the first diagnostic tool since it's non-invasive and doesn't break the skin. This method uses a special magnifying lens with light to examine different skin layers and look for characteristic PN patterns, like pearly white areas with dark crusts.

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While both tests can be effective, dermoscopy is often preferred as the first diagnostic tool since it's non-invasive and doesn't break the skin. This method uses a special magnifying lens with light to examine different skin layers and look for characteristic PN patterns, like pearly white areas with dark crusts.

Key benefits of dermoscopy:
• No risk of infection
• Won't trigger PN flares
• Can examine multiple skin layers
• Can take photos for later analysis
• Checks pigmentation, blood vessels, and keratin levels If further confirmation is needed, a skin biopsy (including punch biopsy) may be performed. This is more invasive and requires removing a small skin sample. The biopsy allows doctors to examine immune cells and keratin levels under a microscope, which can help definitively diagnose PN. However, you may need to avoid topical treatments before the procedure, and some biopsies might require stitches.

September 17, 2025
A MyPrurigoTeam Member

I was not aware of dermascopy. Is this an expensive piece of equipment for a dermatologist to have in the office? I learned from experience with the punch biopsy that there is a need to identify an appropriate lesion from which to take the sample to submit to the laboratory.

September 18, 2025
A MyPrurigoTeam Member

Both biopsies came back nonspecific. I asked what that means, just what it says. I am supposed to take dupixent on this diagnosis?

September 18, 2025
A MyPrurigoTeam Member

Well, I wish the 9 Dermatologists had known of the Dermoscopy! As through the almost 17 years of dealing with this horrible disease PN w/LSC (aka Lichen Simplex Chronicus) I have had a total of 4 biopsies, 3 punch biopsies, and 1 scraping which all of these have created more inflammation of the lesions on my scalp! I mentioned to my present Dermatologist that I am sure I am dealing with the scar tissue from them which has made my scalp much worse from those invasive biopsies, and she agreed! So too late for that now, and then to be diagnosed with Seborrheic Dermatitis has made my scalp worse and definitely my quality of life!

September 18, 2025

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