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A MyPrurigoTeam Subscriber asked a question 💭
October 30, 2025
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What Does Prurigo Nodularis Look Like? Pictures for Reference Read Article...
A MyPrurigoTeam Member

I have PN on my scalp. My dermatologist prescribed various treatments including Dupixent. Dupixent was unsuccessful in treating it. Nemluvio had not yet been approved by the FDA. I was prescribed a combination of topical prescriptions. Currently, I am using Derma Smooth at bedtime and Clobetesol liquid 0.05%. I use Head and Shoulders Bare shampoo because the Bare formula doesn't have extra ingredients in it. The dermatologist recommended N-Acetyl-Cysteine supplement to control the itching which was intense. Heat, humidity, and sweating causes my scalp to flare. I'm planning on making a trip to PA for a dermatology appointment to discuss Nemluvio. I think that the scalp is difficult to manage because I am unable to view the lesions. Currently, the symptoms are under control but not gone.

November 2, 2025
MyPrurigoTeam

Can prurigo nodularis affect your scalp?

Yes, prurigo nodularis can definitely affect your scalp. While it most commonly appears on arms, legs, abdomen, back, and buttocks, many people experience intense itching on their scalp too.

The scalp can be particularly challenging because hair can interfere with applying topical Show Full Answer

Can prurigo nodularis affect your scalp?

Yes, prurigo nodularis can definitely affect your scalp. While it most commonly appears on arms, legs, abdomen, back, and buttocks, many people experience intense itching on their scalp too.

The scalp can be particularly challenging because hair can interfere with applying topical treatments. Scratching an itchy scalp can lead to nodules and scars, with lesions often appearing more commonly on the back of the head. The scratching and rubbing can also damage hair follicles, which may lead to hair loss.

As one MyPrurigoTeam member shared: "Every morning when I wake, there's hair on my pillow. I've been battling this since I was 25. I'm 57 now. My hair is so thin, I call it see-thru hair." Treatment options for scalp itching include shampoos with a pH between 4.5 and 6.0, which can help reduce itchiness. Some members find relief with products like Head & Shoulders or Dove dry scalp shampoo.

Topical treatments containing capsaicin, menthol, or calcineurin inhibitors like tacrolimus can also help. Prescription topical corticosteroids may provide relief too, though applying them to your scalp requires careful technique due to hair getting in the way.

October 30, 2025

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