Hi all, was looking for feedback on itching that is associated with sweating. Ive been on nemluvio for PN since october 2025. Its helped with persistent everyday itching, but I still struggle with intense itching flare ups whenever I eat hot foods/soups, or do physical exercise. Basically anytime my body wants to sweating it brings on and intense entire body itch and this doesnt seem to be helped by nemluvio. This internal heat/sweat based flareup happens pretty much everyday and is the primary… read more
I have flare ups of PN when it is hot and humid. My scalp sweats and then a nodule or nodules appear typically in the occipital region of my scalp. I don't really have a problem with itching since my dermatologist recommended N-Acetyl-Cysteine (NAC 600 mg twice per day) supplement. If you haven't been aware of this supplement, I encourage you to ask your dermatologist about it's usage in regards to PN and itching.
Yes sweat and getting hot starts hurting and burning. I use icepacks to cool off or take a cool shower.
How can you manage intense itching triggered by sweating and rising body temperature with prurigo nodularis?
You're definitely not alone in experiencing this. Heat, humidity, and sweating are well-known triggers that can make PN itching significantly worse, even when other treatments are helping with baseline symptoms.